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PptT inhibitor 8918
CAS No. 65009-19-0
PptT inhibitor 8918 ( Compound 8918 )
产品货号. M15469 CAS No. 65009-19-0
PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PptT inhibitor 8918
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM).
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产品描述PptT inhibitor 8918 (Compound 8918) is a mycobactericidal amidino-urea compound that targets phosphopantetheinyl transferase (PptT, IC50=2.5 uM), shows an MIC90 of 3.1 uM against Mtb H37Rv; also exhibits MIC90s ranged from 0.56-3.0 uM (median 1.5 uM) against 29 clinical isolates of Mtb; inhibits growth of WT Mtb, but not of the pptT mutant W170S or WT Mtb expressing the pptT W170S mutant; kills Mycobacterium tuberculosis (Mtb) by binding and partially inhibiting PptT.
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同义词Compound 8918
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number65009-19-0
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分子量262.36
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分子式C14H22N4O
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Amidino-urea 1-[(2,6-diethylphenyl)-3-N-ethylcarbamimodoyl]urea
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ballinger E, et al. Science. 2019 Feb 1;363(6426). pii: eaau8959. doi: 10.1126/science.aau8959.
产品手册
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